Anima Cocktail Lab sits on Constitucion in Barrio Bellavista, an author bar that Guia Comino covered when it opened in December 2025. The room comes from mixologist Pablo Prufer and runs an experimental list that pairs each drink with a scent.
Who would love it: drinkers who want a laboratory style menu and a sensory hook with their cocktail. Who would hate it: anyone after a straight classics bar, since the point here is the experiment and the concept.
The signature is the scent. El Mostrador reports that every cocktail arrives on a coaster carrying a perfume matched to the drink, so the aroma is built into the serve rather than left to the glass alone.
The room sets the mood. The space reads gothic and elegant with dim light and industrial details, a deliberate frame for a bar whose name means soul or anima in Spanish.
The pricing is part of the pitch. Prufer told local press the bar aims to democratize cocktails, so the laboratory format runs at accessible prices rather than a tasting menu markup.
The kitchen rotates. Chef & Hotel reports the food menu changes every four months under a guest chef, and the first resident, Renzo Tisinetti, built a run of finger food plates with a Spanish and Mediterranean lean.
The schedule is clear. Anima Cocktail Lab opens Tuesday to Saturday from 6:30pm to 3am, which makes it a late option in a neighbourhood that runs into the early hours.
The crowd leans toward cocktail drinkers and the curious. The concept draws people who came for the experiment and the scent pairing, which keeps the room attentive at the bar.
The Bellavista setting frames the night. Constitucion runs through the heart of the neighbourhood, which makes Anima an easy stop on a longer Bellavista route past its restaurants and cocktail rooms.
Anima Cocktail Lab suits a curious date, a late cocktail, or a drinker after something new. Compare the bartender programme at El Sindicato in Santiago and the negroni list at Siete Negronis in Santiago, then read the guide to the best cocktail bars in Santiago and browse more rooms in Barrio Bellavista.
Sources: Guia Comino feature on Anima Cocktail Lab (2025); El Mostrador Revista Jengibre (December 2025); Chef & Hotel report; Anima Cocktail Lab on Instagram.
