Panama City keeps its best bars in Casco Viejo, the colonial Old Quarter that runs from craft rum rooms to rooftop terraces in a few walkable blocks.
This guide covers six rooms the editors rate across cocktails, rum, beer and rooftop views. Each profile is sourced from the venue, local guides and visitor reviews.
Start with a cocktail at The Strangers Club in Panama City, move to rum at Pedro Mandinga Rum Bar in Panama City, then climb to Tantalo Roofbar in Panama City for the skyline.
For beer, La Rana Dorada in Panama City pours the country's pioneering craft pints, while Relic Bar in Panama City hides a courtyard inside a colonial mansion. See how the city compares in our best cocktail bars in Latin America roundup, or browse all cities.